Heinrich Rueeger Selected Research

NB-360

9/2015

A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice.

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Heinrich Rueeger Research Topics

Disease

6	Alzheimer Disease (Alzheimer's Disease) 10/2021 - 05/2003
2	Dementia (Dementias) 11/2018 - 09/2015
2	Amyloid Plaque 11/2018 - 11/2008
1	Neoplasms (Cancer) 01/2022
1	Skin Ulcer 01/2021
1	Wounds and Injuries (Trauma) 01/2021
1	Asymptomatic Diseases 11/2018
1	Neuroinflammatory Diseases 09/2015
1	Infections 07/2006

Drug/Important Bio-Agent (IBA)

2	UmibecestatIBA 10/2021 - 11/2018
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 10/2021 - 11/2008
2	Amyloid (Amyloid Fibrils)IBA 11/2018 - 09/2015
2	Proteins (Proteins, Gene)FDA Link 11/2018 - 11/2008
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2022
1	NB-360IBA 09/2015
1	Amyloid beta-PeptidesIBA 11/2008
1	signal peptide peptidaseIBA 07/2006
1	CholesterolIBA 07/2006
1	Presenilin-1IBA 07/2006
1	Peptide Hydrolases (Proteases)FDA Link 07/2006
1	PresenilinsIBA 05/2003

Therapy/Procedure

3	Therapeutics 01/2021 - 11/2008